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![]() Dogs need to be mentally and physically stimulated, and exploring (especially with their mouth) is a normal behaviour for them, especially when young. In some cases, pica is not caused by disease or stress. It is important to solve this problem as soon as possible, as the behaviour will become more established with time and repetition. In this case you must help your dog to feel more comfortable with these situations. When your dog does not know what to do, he or she may try to chew and eat things to relax. If there is no medical condition causing the pica, it may be that your dog is using pica to to cope with situations where they feel uncomfortable, or when they feel very excited. Dogs that lick surfaces may have some gastrointestinal upset and if this can be resolved the licking will stop. If you are concerned about any behaviour shown by your pet always consult your vet for advice. Eating grass can be considered a relatively normal behaviour in dogs unless your dog is sick before or after doing it or the behaviour is very frequent or changes suddenly (i.e. More questions about your dog's bad eating habits? Contact our Nashua veterinarians to book an appointment today.It is possible for some medical problems to cause pica so it is important that all dogs with this behaviour are examined by a vet. Always separate your dogs at feeding time if you have more than one.Use a slow feeder bowl to restrict quick feedings.You can help prevent canine bloat in your dog with the following methods: ![]() ![]() How to Prevent Canine Bloat Canine bloat is the inflation of the stomach or abdomen in dogs caused by the ingestion of too much food or inedible items.
![]() LEGO® Education WeDo 2.0 is developed to engage and motivate elementary students’ interest in learning science- and engineering-related subjects. This is done through the use of motorized LEGO® models and simple programming. Quoted from “LEGO Education WeDo 2.0 Introduction” document WeDo 2.0 supports a hands-on, “minds on” learning solution that gives students the confidence to ask questions and the tools to find the answers and to solve real-life problems. When our instructors are developing WeDo 2.0 courses, we evaluate both its strength and weaknesses and the following only represents our own opinion. ![]() The mechanical models of LEGO WeDo 2.0 cover some typical mechanical structures, such as gears, bevel gears, rack, worm gears, crankshaft, pulley, belt drive, etc. For the 16 tutorial projects, all of those above simple mechanics have been covered and can be built step by step. ![]() Meanwhile, based on those sample models, students can make freestyle designs to create other mechanical structures.Īlthough LEGO mentions that WeDo 2.0 is targeted to primary 3-5 students. In terms of those mechanical structures, even secondary schoolers could benefit a lot on how to work on those gears, axis, rim, rack, worm gear to design exquisite mechanical structure. Jasper Road and Brewer Road intersection upgrade Hopkins Street and Moore Street intersection safety improvements Highbury Road pedestrian crossing Burwood East Heidelberg Kinglake Road motorcycle safety improvements Glenferrie Road track maintenance road closure Glenferrie Road bridge upgrade works Malvern Anniversary Trail improving connectivity at Toorak RoadĪrundel Road Pedestrian Operated Signals POS Keilorīalnarring Road Merricks North Temporary speed limit changeīell Street bridge, Coburg safety improvement worksīuckley Street and Garnet Street Pedestrian Safety Improvementsīurwood Road and Camberwell Road safety improvements HawthornĬanterbury Road Waterloo Street to Sunset Drive improvementsĬentre Road and Bignell Road intersection safety improvementsĭonnybrook Road bridge maintenance Yan Yean Yarra Street and Ringwood Warrandyte Road maintenance worksīallarat Road and Hulett Street intersection upgradeīlackburn Road and Wellington Road Intersection Safety Improvementsīoronia Road and Lewis Road intersection upgradeīoronia Road and Lewis Road intersection upgrade - Simplified Chinese Western Roads Upgrade road resurfacing on Princes Highway Western Roads Upgrade Road resurfacing on Ballarat Road Western Roads Upgrade Princes Highway Werribee Main Road Western Freeway maintenance works - Vietnamese Western Freeway maintenance works - Punjabi Western Freeway maintenance works - Arabic Upcoming maintenance on Millers Road Blackshaws Road and Grieve Parade Sydney Road pedestrian safety improvements Safer speed limit on Nepean Highway Frankston Repairing landslips on Donna Buang Road and Acheron Way Point Nepean Road pedestrian improvements Point Cook Road and Central Avenue Pedestrian Safety Improvements Moreland Road Pedestrian Safety Improvements Maroondah Highway Black Spur emergency tree removal works Maribyrnong Road signalised pedestrian crossing, Ascot Vale Malvern Road track maintenance and bridge strengthening Maintenance works at Taylors Road and East Esplanade Lower Heidelberg Road Pedestrian Safety Improvements ![]() ![]() Īt the end of 2008, Gianluca Martino's company, Smart Projects, registered the Arduino trademark in Italy and kept this a secret from the other co-founders for about two years. The founding bylaws of Arduino LLC specified that each of the five founders transfer ownership of the Arduino brand to the newly formed company. The manufacture and sale of the boards were to be done by external companies, and Arduino LLC would get a royalty from them. In early 2008, the five co-founders of the Arduino project created a company, Arduino LLC, to hold the trademarks associated with Arduino. It was estimated in mid-2011 that over 300,000 official Arduinos had been commercially produced, and in 2013 that 700,000 official boards were in users' hands. įollowing the completion of the platform, lighter and less expensive versions were distributed in the open-source community. The initial Arduino core team consisted of Massimo Banzi, David Cuartielles, Tom Igoe, Gianluca Martino, and David Mellis. ![]() The new project, forked from Wiring, was called Arduino. In 2005, Massimo Banzi, with David Mellis, another IDII student, and David Cuartielles, extended Wiring by adding support for the cheaper ATmega8 microcontroller. The Wiring platform consisted of a printed circuit board (PCB) with an ATmega128 microcontroller, an IDE based on Processing and library functions to easily program the microcontroller. The project goal was to create simple, low cost tools for creating digital projects by non-engineers. Casey Reas is known for co-creating, with Ben Fry, the Processing development platform. In 2003 Hernando Barragán created the development platform Wiring as a Master's thesis project at IDII, under the supervision of Massimo Banzi and Casey Reas. At that time, the students used a BASIC Stamp microcontroller at a cost of $50. The Arduino project was started at the Interaction Design Institute Ivrea (IDII) in Ivrea, Italy. History Founding The first Arduino ever made The bar was named after Arduin of Ivrea, who was the margrave of the March of Ivrea and King of Italy from 1002 to 1014. The name Arduino comes from a bar in Ivrea, Italy, where some of the project's founders used to meet. Common examples of such devices intended for beginner hobbyists include simple robots, thermostats, and motion detectors. ![]() The Arduino project began in 2005 as a tool for students at the Interaction Design Institute Ivrea, Italy, aiming to provide a low-cost and easy way for novices and professionals to create devices that interact with their environment using sensors and actuators. In addition to using traditional compiler toolchains, the Arduino project provides an integrated development environment (IDE) and a command line tool developed in Go. The microcontrollers can be programmed using the C and C++ programming languages (Embedded C), using a standard API which is also known as the Arduino Programming Language, inspired by the Processing language and used with a modified version of the Processing IDE. ![]() ![]() The boards feature serial communications interfaces, including Universal Serial Bus (USB) on some models, which are also used for loading programs. The boards are equipped with sets of digital and analog input/output (I/O) pins that may be interfaced to various expansion boards ('shields') or breadboards (for prototyping) and other circuits. Īrduino board designs use a variety of microprocessors and controllers. Arduino boards are available commercially from the official website or through authorized distributors. Its hardware products are licensed under a CC BY-SA license, while the software is licensed under the GNU Lesser General Public License (LGPL) or the GNU General Public License (GPL), permitting the manufacture of Arduino boards and software distribution by anyone. Arduino ( / ɑː r ˈ d w iː n oʊ/) is an Italian open-source hardware and software company, project, and user community that designs and manufactures single-board microcontrollers and microcontroller kits for building digital devices. ![]() ![]() ![]() Rage face, Pepe the frog, and Shiba Inu Dog are some famous examples of comic meme stickers. Memes have taken over the internet over the last few years to the point where the biggest companies in the world are using memes for their product marketing. These are the best collection of Anime Stickers you can add to WhatsApp. Iconic dialogues from these characters have a variety of stickers. Anime characters like Naruto, Itachi Uchiha, Goku, Vegeta, Monkey D Luffy, and many more have considerable fan followings worldwide. Anime Stickers WAĪnime, the Japanese type of animation, is prevalent across the globe for its story and visuals. Related Read: How to Fix Custom Stickers Not Showing in WhatsApp 5. Here are some emoji-based colorful sticker packs. Surely, it’s a cool sticker pack to have in your repository. Given that WhatsApp enlarges the size of an emoji when you send a single emoji in a message, Emoji stickers can trick your friend into thinking when they receive a mega-sized emoji icon in the form of a sticker. Emoji stickers are the perfect way for you to slip in a reaction in the chat without making it too eye-catching. These add a whole new expression to an emoji, making it more lively. The good old emojis make for a really cool collection of stickers, especially when you have animated emoji stickers. iOS users can use the pre-made phrase sticker packs mentioned above. Once you select this keyboard, Bobble will show sticker suggestions by picking up the typing words. The app is actually a keyboard, available only for Android on the Google Play Store. You can also try Bobble, a free application that instantly converts your text sentences into a WhatsApp sticker. Not only does it bring in a change, but if the phrase contains some humor or wit, both parties can have a good short laugh! ![]() When a chat starts to feel boring, or if the other person gets way too excited, using Stickers with Phrases is a great way to handle the situation. Here are some popular and funny WhatsApp sticker packs containing WhatsApp sticker pranks. Do try out the ‘Blank Sticker’ prank once! These are some pranks that will surely give your friends a moment to laugh. ![]() WhatsApp animated stickers with a loading animation appear as a pending download, a sticker portraying the ‘Retry’ option of media failure, or a moving insect sticker. Here are some pranks that you can play with WhatsApp stickers. Pranking your friends is the best way to have fun, a giggle for the prankster with the victim’s embarrassment. These are the best Sticker packs of Sports Personalities that you can add to WhatsApp. So, right from Ronaldo’s Siu celebration to some legendary reactions from Kohli on the field, these expressions make for some fun stickers. Sports personalities like Cristiano Ronaldo and Lionel Messi from the world of Football, and many other famous sports figures like Virat Kohli, MS Dhoni, Roger Federer, and many more have many iconic moments while playing their respective sports. Here are some of the best WhatsApp Sticker packs that you can use. Funny stickers for WhatsApp are particularly in vogue and can be further categorized into prank stickers, comic meme stickers, and more. WhatsApp stickers have no limits one can get as creative as they wish with them, which can totally change the course of the conversation. You know, just in case when the chat gets a little overwhelming, and you run out of words. Also, specific sticker packs can be used to end a conversation quietly. So the more custom a sticker gets, the more relatable it becomes, making the conversation much more lively. The best part about WhatsApp sticker packs is the fact that custom WhatsApp stickers can be easily created by normal users, unlike emojis. So when you combine both of them, you get a WhatsApp sticker! Pictures say a thousand words, and a meme can say ten thousand. WhatsApp stickers are a quick way to express your feelings in a conversation without actually having to type anything. How can I add stickers on WhatsApp without app? How can I add stickers on WhatsApp manually? How to create WhatsApp stickers on iPhone? How to create WhatsApp stickers on Android? Which is the best Sticker app for WhatsApp? 10. Personal Stickers – WhatsApp stickers from photos. ![]() ![]() You forge alliances and together you take on your enemies. You do your best to keep your population happy. Range of functionality is comprised of expansion, diplomacy and managing your nation's finances and economy. Form alliances and fight co-op style with the AI and other players for ultimate victory. Wage colossal wars solo, against the AI, or take on your gaming friends in cross-platform multiplayer games. From Rome to Asian nations, you create your own warring experience. Command your armies in one of the many ancient and medieval countries including the Roman Empire, the Inca, France, Russia, Japan or the Chinese Dynasties. Now supports simultaneous 32- and 64-bit apps.Age of Conquest is a turn-based grand strategy wargame. Whether you’re a gamer, a social media enthusiast, or a productivity-focused user, BlueStacks offers a range of features and updates that make your mobile experience on a larger screen even better.īlueStacks requires a PC or Mac with at least 4GB of RAM. In conclusion, BlueStacks is the ultimate solution for anyone who wants to enjoy Android applications on their computer or laptop. In addition, key features like Advanced Keymapping and the Instance Manager are more intuitive and user-friendly than ever before. Its sleek and modern interface is designed to provide a seamless mobile experience on a larger screen. This is particularly useful for multitasking and productivity apps.īlueStacks 5, the latest software version, is faster and lighter than ever. It lets you run multiple apps or games simultaneously on a single machine, allowing you to get more done in less time. This feature makes it easier to perform repetitive tasks or complex maneuvers in games, helping you to level up faster and play more efficiently.īlueStacks’ Multiple Instances feature is another game-changer. With BlueStacks, you can also easily record input sequences and execute them with a single button click using the Macro functionality. So whether you’re playing action-packed or strategy games, you can customize controls to suit your preferences and play like a pro. This feature allows you to assign controls to your mouse, keyboard, or gamepad for more accurate gameplay. So whether using a PC or a Mac, you can enjoy your favorite mobile apps and games on a larger screen with BlueStacks.īlueStacks’ advanced Keymapping feature is perfect for gamers with more precision and speed. One of the most significant advantages of BlueStacks is its compatibility with both Windows and Mac operating systems. ![]() With BlueStacks, you can access thousands of Android apps and games without a mobile device. This is your chance to create your own warring experience, shape the destiny of nations, and prove your strategic prowess.ĭo you want to enjoy the convenience of a larger screen without buying a separate device? Then, look no further than BlueStacks!īlueStacks is a free Android emulator software that allows you to run Android applications on your computer or laptop. ![]() Achieve greatness, claim victory, and etch your name in the annals of history. ![]() Use the map editor and a central server to create and share your own player-modded bundles with the community.ĭownload Age of Conquest IV on PC with BlueStacks today and become the master of empires. Put your strategic skills to the test with a challenging AI that adapts and learns using a genetic algorithm. Join forces with AI or other players in co-op team games, and together, strive for ultimate victory. Wage colossal wars against the challenging AI or compete against your gaming friends in cross-platform multiplayer games, and enjoy endless hours of strategic gameplay. Expand your territory, engage in diplomacy, and manage your nation’s finances and economy.Keep your population happy and forge alliances to take on your enemies. You have complete control over every aspect of your empire. From the grandeur of Rome to the rich heritage of Asian nations, forge your own path to glory. BlueStacks app player is the best platform to play this Android game on your PC or Mac for an immersive Android experience.ĭownload Age of Conquest IV on PC with BlueStacks and command powerful armies as you lead ancient and medieval civilizations, such as the mighty Roman Empire, the Inca, France, Russia, Japan, or the Chinese Dynasties. ![]() Age of Conquest IV is a Strategy game developed by Noble Master Games. ![]() ![]() Putting a Rose Quartz under your pillow allows you to have a peaceful sleep and wake up feeling positive.
![]() Therefore, manipulating the genome is crucial for elucidating the causes of disease and systematically studying the many genes that underlie intracellular processes. Many human diseases, such as cancer, heart disease, and diabetes, are characterized by multifactorial genetic inheritance ( Khera et al., 2018 Ishigaki et al., 2020). Our data indicate that more suitable mutants can be rapidly generated using CRISPR/Cas9-based techniques to study gene function in Dictyostelium. We demonstrate the use of these tools for some candidate genes. We also describe new tools, including double knockouts using a single CRISPR vector, drug-inducible knockouts, and gene knockdown using CRISPR interference (CRISPRi). Herein, we provide a detailed protocol for the CRISPR/Cas9-based method in Dictyostelium. CRISPR/Cas9 techniques not only provide an alternative to homologous recombination-based gene knockouts but also enable the creation of mutants that were technically unfeasible previously. Recently, we have applied CRISPR/Cas9-mediated approaches in Dictyostelium, allowing the rapid generation of mutants by transiently expressing sgRNA and Cas9 using an all-in-one vector. ![]() In the biomedical model organism Dictyostelium discoideum, the methodology for gene targeting with homologous recombination to generate mutants is well-established. The development of new techniques to create gene knockouts and knock-ins is essential for successful investigation of gene functions and elucidation of the causes of diseases and their associated fundamental cellular processes. 2Laboratory for Cell Signaling Dynamics, RIKEN, Center for Biosystems Dynamics Research (BDR), Osaka, Japan.1Department of Biology, Faculty of Science, Toho University, Funabashi, Japan.Processing over a million specimens each year allows us to provide real-time analytics regarding emerging drug use trends, such as our studies published in JAMA and our most recent Millennium Health Signals Report ™.Kensuke Yamashita 1† Hoshie Iriki 1† Yoichiro Kamimura 2 Tetsuya Muramoto 1* Clinical drug testing is used in various healthcare settings to obtain objective information about patients' recent use of prescription medications and illicit drugs. Walton earned his bachelor's degree from Yale University and a Master of Business Administration degree from the Harvard Business School.Ībout Millennium Health Millennium Health is an accredited specialty laboratory with over a decade of experience delivering timely, accurate, clinically-actionable information through our nationwide medication monitoring and drug testing services. Before leading the esoteric businesses at LabCorp, Walton had numerous roles within the company including heading up strategic planning and mergers and acquisitions and served as the company's Chief Information Officer. Prior to that, he held a number of senior leadership positions at LabCorp, most recently as Executive Vice President of the esoteric testing business and as a member of LabCorp's five-person Executive Committee. Walton was previously CEO at Ameritox and Inform Diagnostics and served as a board member at Oxford Immunotec. I am committed to continuing to support our extraordinarily important mission, as well as the market leading lab testing, customer service, reporting, thought leadership, and compliance that the industry has come to expect from Millennium Health." "I feel very fortunate to be joining Millennium Health at such an exciting time in the Company's history. "Medication monitoring and drug testing are critical in helping address some of society's most pressing health care and public health challenges" said Walton. "With over twenty years of experience working in both public and private clinical diagnostics companies, Scott's expertise in strategic planning, mergers and acquisitions, information technology, and operations will be a great addition to the leadership team already in place at the Company." ![]() "We are very excited to have an executive with such deep industry experience as Scott joining Millennium Health as our new CEO," said Andrew Milgram, Chairman of the Board. 26, 2021 /PRNewswire/ - Millennium Health, a national leader in specialty medication monitoring and drug testing, today announced the appointment of Scott Walton as Chief Executive Officer (CEO) effective immediately. ![]() ![]() ![]() If you have any questions, please feel free to contact us by email. Archive file(s) quickly and encrypt the archive file(s).Ĩ. ![]()
![]() ![]() You will be unable to submit a return/exchange request after that 7-day period. From that time, you have 7 days ( including weekends and holidays) to make a return/exchange request. The return window begins when your package is marked "Delivered" by the tracking system. We offer a 7-day return window for most purchases (exclusions listed below). If your order is canceled for any reason before that charge is completed, the amount will show on your payment method as "Pending." That status will go away within 3 to 5 business days, depending on your bank or credit card issuer. Your payment method is authorized at the time of purchase but is only actually charged when the item is being prepared for shipment. You are not charged if an item you order is out of stock.If any information is incorrect on your order confirmation email, please let us know quickly via email, so it can be corrected before shipment. We ship out orders using the exact address information that is provided to us at the time of checkout and cannot make any changes once the package is in-transit.If your event is coming up soon, please contact us before placing your order to discuss options for dresses that may already be in stock or in production. Shipping availability and processing time vary considerably (up to as much as 6 months) for special order items such as bridal and quinceanera dresses, because those types of dresses are custom made-to-order.Expedited and international shipping costs are non-refundable.2nd Day Air Shipping (2 to 5 business days) - $55 for 1 item (additional $5 per item).Ground Shipping (5 to 7 business days) - $30 for 1 item (additional $5 per item).Hawaii and Virgin Islands Shipping Information: 2nd Day Air Shipping (2 to 5 business days) - $40 for 1 item (additional $5 per item).Ground Shipping (5 to 7 business days) - $30 for 1 item (additional $5 per item).Orders over $99 within the continental US ship free via standard ground shipping! Expedited shipping options are available at checkout.In-stock orders are shipped via UPS or USPS within 2 business days. ![]() |
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